THE UNIVERSITY OF NEWCASTLE UPON TYNE DEPARTMENT OF PHARMACOLOGICAL SCIENCES CLINICAL PHARMACOLOGY UNIT Professor J. W. Thompson Dr. C. H. Ashton THE MEDICAL SCHOOL FRAMLINGTON PLACE NEWCASTLE UPON TYNE NE2 4HH TEL: (0191) 232 8511 Ext 7017 CHA.VW 7th February, 1989 [receipt stamp: 08 Feb 89] Miss Debbie Postgate Hallmark Atkinson Wynter Solicitors 379/3881 Brixton Road Brixton London SW9 7DE Dear Debbie Postgate, re: Panos Koupparis I received the various documents relating to your client and am preparing a report. This will take some time and is most unlikely to reach you before 20th February. As you say, the information I have is remarkably short of medical evidence of prescriptions and doses of drugs that Mr. Koupparis claims to have received. In particular, there is no evidence of his having been prescribed diazepam (Valium) by either Dr. Sophocleous or Dr. Evthoka, although Mr. Koupparis claims he was taking it in large doses - upto 100 mg daily. Can he say who was prescribing it? Perhaps he was getting it from another source than the psychiatrists - e.g. from a G.P. Can he supply evidence? (In some countries one can buy it on the counter; I am not sure of the situation in Cyprus). There is also no evidence of prescriptions for chlorpromazine (Largactil) although Mr. Koupparis claims he was taking it. Can he say who was prescribing it? Finally, can he say who prescribed the Mogadon for him in 1982, and the Normison in 1983? It would also be helpful to have a description of Mr. Koupparis' mental state when first seen by Dr. Evthoka. I await the further information which you hope to get from Cyprus. My impression so far is that (even leaving out the drugs mentioned above) Mr Koupparis received grossly excessive doses and mixtures of mind-altering drugs which could well have caused or exacerbated an abnormal mental state. Yours sincerely, C H Ashton C.H.Ashton